As the men of Major Generals George E. Pickett and Isaac R. Trimble, and Brigadier General James Johnston Pettigrew moved forward towards their watchful Union counterparts, they were blessed with occasional respites from the relentless Union cannon fire. As the men from the South approached within 400 yards of the Federal lines on Cemetery Ridge, Northern artillerymen replaced shot and shell with deadly canister rounds. The horrible slaughter from the grapeshot or canister would decimate the Confederate ranks, depriving them of irreplaceable leadership during future campaigns. Although General Pickett would escape unharmed, all three of his Brigadiers would become casualties, two of them losing their lives. General Trimble, who was leading two brigades for the earlier wounded General Pender, would himself be wounded at the Emmitsburg Road, resulting in the amputation of a leg. General Pettigrew would escape with a painful canister shot to his right hand, only to later receive a fatal wound to his abdomen at Falling Waters on July 14th, just 11 days later as the Confederates continued their withdrawal into Virginia.